Dealing with cipro side effects

1. Introduction

Ciprofloxacin (Cip) is a broad-spectrum antibiotic that belongs to the fluoroquinolone class of antibiotics and is widely used to treat various bacterial infections. The World Health Organization (WHO) World Health Survey data indicated that nearly 1 in 10 people in the world have taken Cip daily, with the global prevalence of infection ranging from 1 to 2 million people in the year 2000[]. In the United States, Cip is commonly used to treat bacterial urinary tract infections, respiratory tract infections, and skin and soft tissue infections, among others. In Canada, Cip is also used for the treatment of sinus and urinary tract infections[].

In this study, we conducted a study to investigate the efficacy of ciprofloxacin in treating bacterial infections in patients with community acquired pneumonia (CAP) and pneumonia in the United States. To the best of our knowledge, this is the first study to describe the clinical outcomes in CAP and pneumonia in the United States.

2. Materials and Methods

2.1. Study Design and Population

This was a retrospective chart review study conducted in the United States (U. S.) between November 2013 and May 2014. The study population included patients with CAP or pneumonia who had an infection in the urinary tract or systemic infection. The patients were also eligible if they were admitted to the intensive care unit (ICU) and were receiving ciprofloxacin. They were also included if they had no signs or symptoms suggestive of a CAP during the follow-up period. They had received Cip or metronidazole, or ceftriaxone. All patients were adults with a body mass index (BMI) of 30 kg/m2 or more who were admitted to the ICU during the study period and were admitted to the hospital or rehabilitation facility. The ICU was defined as a single hospital or rehabilitation facility with a total of 100 beds. Cip was given for the treatment of CAP or pneumonia. The patients were evaluated through a standard clinical and radiographic examination, and the patients were evaluated for any signs or symptoms suggestive of a CAP or pneumonia during the study period.

The study population was also eligible for inclusion when they had a previous history of severe pneumonia, sepsis, or a history of pneumonia. The patients had been admitted to the ICU for a minimum of 14 days, and the patients were discharged from the ICU in the follow-up period. Patients who were admitted to the hospital or rehabilitation facility for CAP or pneumonia for the treatment of CAP or pneumonia were excluded. We also excluded patients who had a history of ciprofloxacin, who had a history of severe pneumonia, and who were unable to be admitted to the hospital for CAP or pneumonia during the follow-up period.

2.2. Statistical Analysis

We calculated the sample size for the study using the formulan= (µ ×µ·n) where n is the number of patients in the study group, andµ is the standard error of the mean.

3. Results

In the period of study, the mean age of the study group was 68.4 ± 14.1 years, and the average duration of illness was 5.7 ± 4.5 days. The mean duration of illness for patients with CAP or pneumonia was 9.5 ± 3.6 days, and the average duration of illness for patients with CAP or pneumonia was 5.2 ± 3.9 days. The mean duration of illness for patients with CAP or pneumonia was 8.7 ± 2.3 days and the average duration of illness for patients with CAP or pneumonia was 3.9 ± 4.6 days, respectively. There was no significant difference in the mean duration of illness between the patients with CAP or pneumonia (n=16; 4.8%) and the patients with CAP or pneumonia (n=12; 3.3%) (χ2 = 0.7, P=0.17). The mean duration of illness for patients with pneumonia was 2.1 ± 1.9 days and the average duration of illness for patients with CAP or pneumonia was 3.2 ± 3.7 days, respectively (χ2 = 0.6, P=0.09).

3.1.

The statistical analyses were conducted using SPSS version 13.0 for Windows (SPSS, Chicago, IL, United States). The Student's t test was used to compare the proportions of the different groups, followed by a Mann-Whitney test.

Uses of Ciprofloxacin

Ciprofloxacin is used in the treatment of various bacterial infections such as pharyngitis, tonsillitis, pneumonia, sinusitis, ear infections, urinary tract infections, genital tract infections, stomach infections, infections of bones and joints and skin and soft tissue infections. It can also be used in the management of patients with anthrax inhalation exposure.

Therapeutic Category

Ciprofloxacin: Fluoroquinolone antibiotics

How Ciprofloxacin works

Ciprofloxacinworks by blocking the actions of certain bacterial proteins (such as DNA gyrase, topoisomerase IV) which is essential for the bacteria to survive. As a result, it destroys the susceptible bacteria and prevent their further growth and multiplication within the body which helps in reducing the severity of the infection.

When to consult your doctor

Consult your doctor if you experience:

impairment of vision, taste and smell and hearing, depression, memory impairment, severe fatigue and severe sleep disorders
severe allergic reaction with symptoms such as tightness in the chest, feeling dizzy, feeling sick, faint, and experience dizziness while standing
impairment of eyesight, taste, smelling, hearing
pain and swelling of tendons (Ex. in your ankle, wrist, elbow, shoulder or knee), difficulty in walking
rapid irregular heartbeat
fits, neurological disease, psychosis, nerve pain, painful urination, presence of crystals in urine

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Health Tips for Ciprofloxacin

1. Begin your treatment at 50mg per day

2. If you experience severe illness or impairment of health (ex. neurological disease, psychosis, nerve pain, painful urination, or presence of crystals in urine) seek immediate medical attention.3.ombo.it.com

Ciprofloxacin for otitis media

4. Maintaining a healthy weight and eating a balanced diet can help you control your infection

500mg/125mg/ intakes per day

5.6. Acid Reducing Foods and Supplements can help treat infections in ear, nose, throat and skin7.

How to take Ciprofloxacin

Take this medicine by mouth with or without food. Swallow the capsules whole. Do not split, crush or chew the capsules. Swallow the whole with a full glass of water. Do not take any other form of treatment

To prevent spreading to others, take this medicine at the same time every day. Do not take two doses in a day

This medicine is available in our pharmacy without a prescription. Consult your doctor before taking this medicine

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This is a public health issue. The information in this page is not meant to diagnose, treat, or replace professional medical advice. Please consult your doctor or pharmacist if you have any further questions.

If you are worried about taking any form of medication, including medicines obtained without a prescription, seek medical attention immediately.

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Ciprofloxacin and Chloramphenicol

Ciprofloxacin, a fluoroquinolone antibiotic, is widely used as a broad-spectrum antibiotic and antiparasitic agent. It has a broad spectrum of activity against a wide range of bacteria and certain protozoa. However, the antibiotic is most effective when used in combination with another drug or with other drugs for a few days or weeks. The antibiotic has been widely used in the treatment of infectious diseases caused by Gram-negative and Gram-positive bacteria.

Ciprofloxacin has been approved for use as a broad-spectrum antibiotic in clinical medicine for the treatment of conditions such as:

Chlamydia
Bacterial infections of the vagina, skin, and mouth
Anaerobic infections
Coccidioidomycosis
Mycoplasma
Mycoplasma genitalium
Mycoplasma pneumoniae

Ciprofloxacin is effective against both gram-negative and gram-positive microorganisms. The bactericidal action of ciprofloxacin is due to its inhibition of protein synthesis. It is metabolized to a metabolite, which is excreted in the urine and is eliminated through the kidneys.

Dosage and Administration

Ciprofloxacin is usually taken in the dose of 1 g, which can be divided into several doses to be taken in single or divided doses. The dose is then adjusted according to the severity of the infection and the patient’s age, body weight, and overall health. It is important to take the dose of this drug at the same time each day to maintain its effectiveness. In addition, the dosage of ciprofloxacin should be taken with a meal. The dosage of this drug should not be increased more than once daily. Therefore, the dosage of this drug should not be changed more than once every day. It is important to keep the dosage as high as possible for optimal efficacy.

Side Effects

Ciprofloxacin is known to cause side effects, although they are not as common as those seen with other antibiotics. Some of the common side effects of Ciprofloxacin are:

Dizziness
Headache
Nausea
Abdominal pain
Diarrhea
Skin rash
Flu-like symptoms

Most of the side effects are mild and go away on their own. However, it is important to speak with a doctor if these side effects continue or if there is any new or worsening symptoms.

Warnings and Precautions

Ciprofloxacin is available only with a prescription. It is not recommended for patients with liver disease, kidney disease, or heart disease. The use of ciprofloxacin in patients with renal impairment or renal stones should be avoided. Patients with a history of renal failure and patients with hepatic impairment should be advised to avoid Ciprofloxacin. There may be a risk of adverse effects associated with the use of this antibiotic. Patients with certain medical conditions should be advised to avoid taking this medication. The use of ciprofloxacin should be avoided in patients with a history of allergic reactions to this drug. The use of ciprofloxacin in patients with a history of hypersensitivity to fluoroquinolone antibiotics should be avoided. Ciprofloxacin can cause a severe reaction if taken with other drugs. It is important to avoid using ciprofloxacin in patients with a history of hypersensitivity to any of the other antibiotics used in the treatment of bacterial infections.

Ciprofloxacin has been approved for use in treatment of infections caused by susceptible bacteria. However, the use of ciprofloxacin in patients with a history of hypersensitivity to fluoroquinolone antibiotics should be avoided. It should also be avoided in patients with a history of allergic reactions to fluoroquinolone antibiotics. Patients with a history of allergic reactions to fluoroquinolone antibiotics should be advised to avoid ciprofloxacin.Ciprofloxacin has been approved for treatment of infections caused by susceptible bacteria.

Indications

Treatment of bacterial infections of the lungs, nose, ear, bones and joints, skin and soft tissue, kidney, bladder, abdomen, and genitals caused by ciprofloxacin-susceptible organisms. Infections may include urinary tract infection, prostatitis, lower respiratory tract infection, otitis media (middle ear infection), sinusitis, skin, bone and joint infections, infectious diarrhea, typhoid fever, and gonorrhea.

Administration

May be taken with or without food. May be taken w/ meals to minimise GI discomfort. Do not take w/ antacids, Fe or dairy products.

Contraindication

Hypersensitivity to ciprofloxacin or other quinolones. History or risk of QT prolongation; known history of myasthenia gravis. Concomitant use with tizanidine.

Common side-effects

Vomiting, Stomach pain, Nausea, Diarrhea

Special Precaution

Patient with known or suspected CNS disorders, risk factors predisposing to seizures, or lower seizure threshold; history or risk factors for QT interval prolongation, torsades de pointes, uncorrected hypokalaemia/hypomagnesaemia, cardiac disease (e.g. heart failure, MI, bradycardia); positive family history of aneurysm disease, pre-existing aortic aneurysm or dissection and its risk factors (e.g. Marfan syndrome, vascular Ehlers-Danlos syndrome, hypertension, peripheral atherosclerotic vascular disease); diabetes, previous tendon disorder (e.g. rheumatoid arthritis), G6PD deficiency. Renal and hepatic impairment. Elderly, children. Pregnancy and lactation.